InfinityLab Quick Change Solvent Purifier

An LC solvent purifier, or HPLC solvent cleaner, is a solvent cleaning cartridge designed to reduce the problems caused by HPLC solvent impurity and eliminate ghost peaks.

The Agilent InfinityLab Quick Change Solvent Purifier removes chemical solvent impurities from mobile phases by trapping interfering mobile phase contaminants, which could cause unwanted ghost peaks during HPLC-UV gradient runs.

InfinityLab Quick Change Solvent Purifier
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Features

  • Solve the problem of HPLC solvent impurity
  • Eliminate ghost peaks
  • Three solvent cleaning cartridge dimensions are available
  • Tool-free cartridge replacement
  • pH range: 1–13
  • Pressure limit: 1300 bar
  • For gradient reversed-phase UHPLC-UV applications
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How It Works

Positioning of the Quick Change Solvent Purifier in the HPLC pump flow path

Unwanted contaminants in HPLC mobile phases can show up in chromatograms as “ghost peaks”, which negatively impact detection limits or correct peak integrations.

Use Agilent’s InfinityLab Quick Change Solvent Purifier during time-consuming troubleshooting to identify and eliminate HPLC eluent related issues. This HPLC solvent cleaner should be installed outside of the sample flow path, between the pump gradient mixer and the autosampler, to remove chemical impurities in HPLC solvent.

Solvent purification performance

The InfinityLab Quick Change Solvent Purifier can effectively eliminate impurities due to its superior adsorption efficiency. This chromogram demonstrates its purification performance for an acetonitrile/water gradient targeting chemical contaminant.

Blue line: Working principle of impurity trapping with installed InfinityLab Quick Change Solvent purifier, 2.1 x 20 mm, for an acetonitrile/water gradient.

Finger-tight cartridge replacement

The cleaning cartridge of InfinityLab Quick Change Solvent Purifier is replaceable, which lowers the overall cost and reduces the environmental impact. The tool-free design provides a fast and effortless way to replace, or switch between, cartridges.

Users just need to loosely screw the connectors onto each end of the cartridge before tightening them simultaneously by hand until a "click" is heard or felt. The "click" indicates the maximum limit of torque that should be applied, and provides a sealing of up to 1300 bar.

Product Description and Part Numbers

Part Number
DescriptionContents
5067-1620 InfinityLab solvent purifier assembly 2.1x20mm
Holder Kit + 1 cartridge
5067-1621 InfinityLab solvent purifier assembly 3.0x75mm
Holder Kit + 1 cartridge
5067-1622InfinityLab solvent purifier assembly 4.6x50mmHolder Kit + 1 cartridge
5067-1623 InfinityLab solvent purifier cartridge 2.1x20mm, 1 EA
Replacement cartridge, 1/pk
5067-1625 InfinityLab solvent purifier cartridge 3.0x75mm, 1 EA
Replacement cartridge, 1/pk
5067-1627 InfinityLab solvent purifier cartridge 4.6x50mm, 1 EA
Replacement cartridge, 1/pk
5067-1624 InfinityLab solvent purifier cartridge 2.1x20mm, 5/pk
Replacement cartridge, 5/pk
5067-1626 InfinityLab solvent purifier cartridge 3.0x75mm, 5/pk
Replacement cartridge, 5/pk
5067-1628 InfinityLab solvent purifier cartridge 4.6x50mm, 5/pk
Replacement cartridge, 5/pk

Optional products

5005-0057Capillary, Stainless Steel, 0.17 × 160 mm, SL/SL1/pk
5004-0011Capillary, Stainless Steel, 0.12 × 160 mm, SL/SL1/pk
5432-0062InfinityLab Cartridge Holder Clip1/pk
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Agilent InfinityLab

Quick Change Solvent Purifier User Guide