Nicoya Alto SPR

Why Teach SPR in Research & Academia?

SPR is the gold standard technique for measuring binding kinetics in both industry and academia. From discovering new drugs to gaining a better understanding of diseases, SPR is used by thousands of biotechnology companies and every pharmaceutical company in the world. Students who graduate with experience using cutting-edge techniques like SPR will be best prepared to start their career in industry or continue to do research in the academic world.

• Accelerate your drug discovery research Alto’s flexibility enables it to be a true one-size-fits-all instrument, reducing the time and cost of your research.
• Optimize easily with Alto Cartridges - the first ever SPR sensor integrated with fluidics.
• Cloud-based and AI-powered to streamline your experiments

Why SPR? SPR is becoming a standard technique available in every single biochemistry lab

• Real-Time Monitoring Provides binding kinetics (on/off rates, yes/ no binding and affinity values).
• Label-Free Detection Avoid spending time and money on expensive labeling reagents and protocols.
• Conserve Precious Samples Save money using low sample volumes and concentrations.
• Reusable Sensor Chips Regeneration buffers are used to disrupt the interaction between the analyte and ligand.
• Complex Sample Testing Test crude samples to reduce time and cost associated with purification.
• Reliability and Accuracy Obtain accurate results from repeatable measurements associated with purification.

Advantages of using DMF-powered SPR

• Decoupling of flow rate and sensor position from dispersion, increasing data quality.
• 500X less sample volume required - get full kinetics from a 2ul sample volume.
• Decoupling of interaction time from sample volume, increasing assay flexibility.
• Automated serial dilutions - reducing human error and saving time.
• Flexible high-throughput capabilities with many different assay formats available.
• Ability to implement end-to-end assay automation.
• No clogging, leaking, or contamination as there are no fluidic pathways in the instrumentation.
• Near instantaneous transition times between buffer and sample.
• Flexible fluidic processes enabling on-line, real-time optimization.
• Minimal moving parts so extremely low possibility of mechanical failures.