Sievers Soleil Rapid Bioburden Analyzer

Improve decision-making and alleviate risks throughout manufacturing with the Soleil RMM

With the Sievers Soleil Bioburden Analyzer you can rapidly:

• Monitor critical control points in your water system
• Test intermediates and in-process samples
• Confirm cleaning validation / sanitization of equipment
• Screen incoming raw materials on the receiving dock Perform environmental monitoring of process areas

How would this impact your contamination control strategies? How would this change your operations?

Traditional bioburden testing methods are too slow for effective process monitoring and product release, with plate and membrane filtration methods taking days for results. With the Sievers Soleil Rapid Bioburden Analyzer, you can finally get results in <45 minutes, with data correlating to plate counts. The Soleil is a first of its kind Rapid Microbiological Method (RMM) that uses unique reagents, viability stains, and high throughput flow cytometry to distinguish between viable cells and abiotic particles.

Stop waiting for plate counts! The Sievers Soleil allows you to easily improve your operations, alleviate risk, and remove the bioburden testing bottleneck in product release.

Features & Benefits

• Obtain near real-time bioburden data that correlates to plate counts
• Less than 45-minute total time to result (TTR) for the first sample, and even faster for subsequent samples
• Make fast decisions about the manufacturing process to reduce risk and increase cost savings
• Release products with confidence and remove the bioburden testing bottleneck
• Monitor contamination control processes within water systems, cleaning validation, environmental monitoring, raw materials, and in-process samples
• Reduce costly waste such as discarded product and process inefficiencies
• Perform testing in the lab or at-line throughout manufacturing (can be easily transported to different locations!)
• Easily perform testing with only three pipetting steps (operator hands-on time <5 minutes per sample)
• Simplified, high throughput testing for sample volumes 20-100 mL
• Detect viable cell counts from Gram-negative bacteria, Gram-positive bacteria, yeast, and mold
• Distinguish between viable cells and abiotic particles using proprietary fluorescent stains and high-throughput flow cytometry to ensure accuracy and sensitivity
• Measure not only water, but also complex samples including drug substances, culture media, plastics, and more

Rapid Bioburden Analysis with Sievers Soleil